Monitoring of Monosodium Urate Crystallization for the Detection of Crystal Arthropathies in Human Joints
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Multidisciplinary Digital Publishing Institute Proceedings
A piezoelectric tuning fork sensor is evaluated as a physical excitation and sensing device aiming at the detection of crystals and their nucleation behavior in joint fluids, as observed in gout. This device allows to study the crystallization tendency at varying temperatures or at increased uric acid concentrations as predominant in real human joints. In this work, a tuning fork resonator is characterized to enable spatially resolved viscosity and density measurements by calculating the mode shape of the vibration from resonance frequency measurements when immersed in test liquids.