Andreas Grimmer, Werner Haselmayr, Robert Wille,
"Automated Dimensioning of Networked Labs-on-Chip"
, in IEEE Transactions on Computer Aided Design of Integrated Circuits and Systems (TCAD), 2018, ISSN: 0278-0070
Original Titel:
Automated Dimensioning of Networked Labs-on-Chip
Sprache des Titels:
Englisch
Original Kurzfassung:
Two-phase flow microfluidics is a sophisticated and
frequently applied Labs-on-Chip technology as they allow to
automatically conduct medical/biochemical experiments. In this
technology, small volumes of reagents, so-called droplets, flow
in an immiscible continuous flow inside closed channels making
it particularly biocompatible. In the recent past, this
technology was extended by a concept allowing to passively
navigate droplets through the system ? leading to so-called
Networked Labs-on-Chips (NLoCs). After the design of an NLoC
architecture which defines the comprising connectivity between
components and, by this, how the considered medical/biochemical
experiments are supposed to be realized, the question remains
how to properly dimension the used components, i.e. especially
how to dimension the used channels. However, this is a challenging
task which is conducted manually thus far and frequently
leads to specifications that do not work as intended. In this
work, we are addressing this issue by providing the designer
with methods that allow to (1) automatically validate whether a
chosen specification of an NLoC indeed works as intended as well
as (2) automatically dimension NLoCs. Case studies demonstrate
the importance and usefulness of the proposed methods for
determining proper specifications of NLoCs.
Sprache der Kurzfassung:
Englisch
Journal:
IEEE Transactions on Computer Aided Design of Integrated Circuits and Systems (TCAD)
Forschungs-