Gerold Fink, Medina Hamidovic, Werner Haselmayr, Robert Wille,
"Automatic Design of Droplet-Based Microfluidic Ring Networks"
, in IEEE Transactions on Computer Aided Design of Integrated Circuits and Systems (TCAD), 2020, ISSN: 1937-4151
Original Titel:
Automatic Design of Droplet-Based Microfluidic Ring Networks
Sprache des Titels:
Englisch
Original Kurzfassung:
Droplet-based microfluidic networks allow to process biological or medical samples by standard unit operations
such as mixing, incubating, sorting, or sensing. However, many of
these networks usually perform such operations in a pre-defined
way and, thus, lack in their flexibility. To overcome this problem,
ring networks are used, since they allow to execute multiple
operations in a row. But while several concepts and also prototypical implementations exist that realize such ring networks,
the design process for them is still mainly conducted manually
thus far. This is a severe drawback since various aspects such as
the dimensions of the channels, the effects of droplets, the used
fluids, the volumetric flow rates inside the channels, etc. have
to be considered for this purpose. In this work, we propose
design automation methods which address this problem. The
proposed solution will automatically generate a proper design
as well as correspondingly needed droplet sequences. A case
study demonstrates the applicability of the resulting methods
and simulations confirm the validity of the proposed approach.
Sprache der Kurzfassung:
Englisch
Journal:
IEEE Transactions on Computer Aided Design of Integrated Circuits and Systems (TCAD)
Forschungs-