Tim Gläsel, Marko Hapke,
"Cobalt-catalyzed [2+2+2] cycloaddition reactions"
, in Corinne Gosmini / Ilan Marek: The Chemistry of Organocobalt Compounds, Serie Patai's Chemistry of Functional Groups, John Wiley & Sons, Ltd., Hoboken, NJ (USA), 2024, ISBN: 978-1-119-69201-0
Original Titel:
Cobalt-catalyzed [2+2+2] cycloaddition reactions
Sprache des Titels:
Englisch
Original Buchtitel:
The Chemistry of Organocobalt Compounds
Original Kurzfassung:
Cobalt-catalyzed [2+2+2] cycloaddition reactions belong to the foundation inventory of the cyclotrimerization reactions since the first systematic investigation by Reppe and Schweckendiek for homogeneous nickel-based catalyst systems. Currently, cyclotrimerizations
can be catalyzed or mediated by a very large number of transition metal complexes, with a focus on the late transition metals of Groups 8?10. The broadness of its scope on the side of the catalysts as well as substrates and achievable synthetic targets is impressively documented in a monography3. Mostly, carbo- and heterocyclic compounds are made from alkynes, nitriles, and other heterocumulenes by this approach, including the stereoselective assembly of chiral molecules. [2+2+2] Cycloaddition reactions including cobalt-catalyzed reactions have been compiled in frequent reviews and devoted book chapters, most recently by Gandon and by Hapke and Gläsel. The present chapter compiles early discoveries and findings as well as recent developments and concepts in cobalt-catalyzed cyclotrimerizations.
Forschungs-