Spin-noise-detected two-dimensional NMR at triple sensitivity
Sprache des Vortragstitels:
BISSL (Bilateral Impromptu Symposium (Stockholm-Linz) on NMR Spectroscopy
Sprache des Tagungstitel:
This talk focuses on our groups? latest publication on two-dimensional spin noise
spectroscopy. The presentation reveals the key findings along the way to a fully us-
able two-dimensional experiment and gives insight into some of the problems encoun-
tered during the development. The abstract of the underlying paper is as follows:
The A major breakthrough in speed and sensitivity of 2D spin-noise-detected NMR
is achieved owed to a new acquisition and processing scheme called ?double block
usage? (DBU) which utilizes each recorded noise block in two independent cross cor-
relations. The mixing, evolution and acquisition periods are repeated head-to-tail
without any recovery delays and well-known building blocks of multi-dimensional
NMR (constant-time evolution and quadrature detection in the indirect dimension as
well as pulsed field gradients) provide further enhancement and artifact suppression.
Modified timing of the receiver electronics eliminates spurious random excitation.
We achieve a threefold sensitivity increase over the original snHMQC experiment
(K. Chandra et al., J. Phys. Chem. Lett. 2013, 4, 3853) and demonstrate the
feasibility of spin-noise-detected long-range correlation.